ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

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ETNK1 mutations are recurrent in leukemia but how they Myrrh contribute to oncogenesis is still unclear.Here, the authors show that ETNK1 mutations SUPER MULTI-WITH IRON increase mitochondrial activity, ROS and H2AX levels and that these effects can be rescued upon phosphoethanolamine supplementation.